GeneWerk GmbH (Germany) – www.genewerk.de
SCIDNET Principal Investigator: Manfred Schmidt (email@example.com)
GENEWERK is a SME and was founded as a spin-off of the German Cancer Research Center (DKFZ), Heidelberg, Germany in 2014 by C. von Kalle, M. Schmidt, A. Deichmann and DKFZ. The team has 20 years of experience in the area of hematology, oncology, virology and vectorology with focus on integration site analysis, high throughput sequencing, whole genome sequencing and bioinformatics. The invention and further development of Linear Amplification-Mediated PCR (LAM-PCR) by Manfred Schmidt and Christof von Kalle allows the highly sensitive identification and sequencing of unknown, flanking DNA or RNA sequences, which became the gold standard in gene therapy vector safety studies. GeneWerk GmbH provides custom-tailored services for the assessment of the safety of viral vectors in the context of gene therapy trials, for determination of the immune cell receptor repertoire and for the development of bioinformatic tools for NGS sequence analyses.